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Vitamin B2 (Riboflavin 5 Phosphate) (Pot of 60 capsules)

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Vitamin B2 (Riboflavin)

Both FAD and FADH2 are manufactured in the cells once Vitamin B2 (Riboflavin) reaches the small intestine, so anyone on a good diet will be able to make FAD and FADH2 themselves so we recommend Riboflavin 5 Phosphate.

If their diet is poor, we recommend that a multivitamin (nutrimax) be taken in conjunction with the Riboflavin 5 Phosphate to ensure all co-factors are present for absorption.

Vitamin B2 is one of the 8 water-soluble B vitamins, meaning the body cannot store them. Riboflavin is destroyed by light and heat and in an alkaline medium. It is absorbed in the upper part of the small intestine, is increased with food and delayed on an empty stomach. There is decreased absorption in cases of gall bladder or liver disease and are associated with decreased dietary intake of meat and dairy products.

Folate and Vitamin B6 (Pyridoxine) need R5P for conversion to their bioavailable forms, Methyltetrahydrofolate and Pyridoxal 5 Phosphate respectively. The active forms (the forms in which the body uses them) of Riboflavin are synthesised in the mitochondria, forming Riboflavin 5 Phosphate which is then converted further to Flavine Adenine Dinucleotide (FAD) Metabolics Vitamin B2 is in its bioavailable form Riboflavin 5 phosphate. What does Vitamin B2 do?

  • It contributes to normal energy yielding metabolism - Vitamin B2 is required in its coenzyme form (FAD) for participation in the Citric Acid cycle to produce energy.
  • It contributes to normal functioning of the nervous system - Again in its Coenzyme form, FAD , Vitamin B2 is needed for the monoamine oxidase enzyme, which functions in the metabolism of neurotransmitters ( brain chemicals ) for normal functioning of the nervous system.
  • It contributes to the maintenance of normal red blood cells - Vitamin B2 improves iron absorption and riboflavin deficiency induces anaemia , where there are immature red blood cells.
  • It contributes to the maintenance of normal skin and mucous membranes–both acute and chronic deficiencies result in mucocutaneous lesions that disappear after adequate doses of B2 are given.
  • It contributes to the maintenance of normal vision- Riboflavin deficiency is associated with decreased activity of the enzyme glutathione reductase, the enzyme responsible for the production of glutathione. Reduced glutathione protects the lens of the eye from oxidative damage and is decreased in cataracts. Riboflavin deficiency can cause conjunctivitis with vascularisation of the cornea and opacity of the lens (cataracts).
  • It contributes to the normal metabolism of iron. Iron metabolism is impaired in riboflavin deficiency. The utilisation of iron reserves from the intracellular protein ferritin requires riboflavin. Riboflavin is required for haemoglobin synthesis.
  • It contributes to the protection of cells from oxidative stress. Vitamin B2 participates in many reactions where the cofactors P-5-P and FAD act as electron carriers, protecting the DNA, proteins and lipids from oxidative damage.
  • It contributes to the reduction of tiredness and fatigue As Vitamin B2 is involved in manufacturing energy adequate doses of B2 contribute to normal metabolism resulting in energy.

    Deficiency of Vitamin B2 Clinical signs and symptoms may appear 3-8 months after deficiency. These include sores at the corners of the mouth, sore tongue, dermatitis numbness of the hands or decreased sensitivity to touch, temperature and vibration and visual changes. There may be the tiredness and fatigue associated with anaemia. Alcohol decreases the bioavailability and absorption of riboflavin.

  • Vitamin B2 (Riboflavin 5 Phosphate)

    Recent customer reviews

    1. I was advised to take this product together with zinc sulphate when I was confusingly...
      Jet | (12/07/2015)
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    One capsule contains: 47.5 mg Vitamin B2

    Ingredients: Cellulose, Riboflavin 5 Phosphate.

    Customer Reviews

    1. Very effective, Review by Jet
      Speed of delivery

      I was advised to take this product together with zinc sulphate when I was confusingly diagnosed as being hypothyroid. The kineseologist I saw recognised that I could be suffering from mercury filling toxicity from old leaky fillings. He recommended the Metabolics company - and I thought - o.k. - lots of practitioners have their favourite companies that they get a discount from but the supplements aren't necessarily effective. I wasn't sure that most brands of supplements were effective.

      However as a therapist myself and someone who has a body that is sensitive to the effects of substances I put into it - I began to feel its good effects shortly after taking the product and within a few days even what was diagnosed as hypothyroidism began to change. I feel this company has high standards of processing their supplements and I'm surprised that no one has written reviews in the review area of these pages.

      Best wishes to you Metabolics,

      (Posted on 12/07/2015)

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    © Metabolics ltd, 2014. All rights reserved. Metabolics is a limited company registered in England and Wales 2844683. VAT registration number GB 639 3495 03.

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