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Sunlite is a unique combination of ingredients known to protect the skin against harmful radiation from the sun. It is a mix of powerful antioxidants that have been demonstrated to quench free radicals in the skin created by UVA and UVB radiation in order to reduce or prevent damage to the epidermal and collagen cells in the skin. This should be taken in conjunction with a good quality omega 3 oil such as Metabolics Omega 3 or Metabolics Krill Oil to aid cellular protection against lipid peroxidation. Sunlite does not interfere with the body’s natural Vitamin D production as do topical sun creams.
Natural sunlight is essential for our production of Vitamin D, essential to our health and 90% of Vitamin D is obtained from sunlight. 20 minutes of sun exposure can produce 20,000 IU Vitamin D. However Sunlight can also be very damaging.
In order to understand how sunlight can be damaging we first need to understand UVA and UVB radiation.
Part of the suns electromagnetic rays are made up of Ultrtraviolet A (UVA) and Ultraviolet B (UVB) radiation, both of which can damage skin.
UVA radiation is a longer wave length than UVB and travels deeper into the skin, creating free radicals and reactive oxygen species (ROS) .These not only damage the DNA, but can damage collagen and elastin and can travel through the body creating damage in other areas. The free radical damage can result in sunburn, premature skin aging, wrinkles and sun spots, suppressed immune system and DNA mutations that may increase the risk of developing cancer.
UVB radiation has a shorter wavelength than UVA and damages the DNA directly. When UVB radiation hits a strand of DNA, compounds known as thymine and cytosine dimers are created, which can usually be repaired. However long exposure and damage can lead to cell death (sun burn) and inflammation, and occasionally mutation which over time may cause cancer. Non melanoma skin cancer is the most common cancer in humans and malignant melanoma one of the most deadly. UVB triggers the release of immunosuppressive proinflammatory cytokines which could lead to DNA damage.
Photocarcinogenesis and photoageing are the two types of skin damage that occur as a result of dermal extracellular matrix degradation resulting from oxygen and superoxide, as well as hydroxyl and peroxyl radicals .These are believed to promote lipid peroxidation, protein oxidation and cross-linking, enzyme inactivation and DNA damage.
The intensity of UVA and UVB varies throughout the day. The amount of longer wavelength, high intensity UVA remains much the same whatever time of day or time of year, whereas the shorter wave length, lower intensity UVB is partially blocked by the Earth's atmosphere and the strength of UVB reaching the skin varies greatly throughout the day, maximising when the sun is overhead (shortest distance of the rays through the atmosphere, and throughout the year, maximising during the summer months in the Northern Hemisphere and vice versa in the Southern. It is easiest to burn at midday but damage can be sustained from any sun exposure. The longer the exposure, the greater the potential for damage. Skin damage can be cumulative and potentially permanent resulting in aging and irreversible changes to the skin.
How do we tan?
This process is called melanogenesis and usually takes 2-3 days.Specialist cells in the skin called melanocytes produce a pigment known as melaninin released in small packets known as melanosomes. This is taken up by specialist skin cells known as keratinocytes, which migrate to the surface of the skin creating the “tan” colour. The more melanin (the greater the tan!), the less UV radiation can penetrate the skin and the greater the potential protection from further damage. When the UVB damages the melanocytes creating the pyramidine dimers, melanocytes are triggered to produce more melanin. UVA radiation does not stimulate melanogenesis but does release the pre-existing melanin from melanocytes, resulting in a short lived tan. Basically,the greater the tan, the greater the DNA damage.
Vitamin D production
Vitamin D is a very important steroid vitamin and prohormone, required for the absorption of calcium and phosphorus, optimum immune function, necessary for brain function, linked to maintaining a healthy body weight, decreased incidences of cancer in people with adequate levels of Vitamin D. It is very important in the regulation of a number of genes.
When UVB light of wavelength 270-300nm hits a molecule in the skin that would normally be converted to cholesterol (7-dehydrocholesterol), it is converted to previtamin D (Peak vitamin D production occurs between 295-297nm). This is then converted to Vitamin D (cholecalciferol) over 12 days and enters the blood stream . It is then transported to the liver where it is converted into 25-hydroxycholecalciferol (calcidiol) and stored. Eventually it is transported to the kidneys where it is converted to 1,25-dihydroxycholecalciferol (also called calcitriol) its final, active form.
Topical protection from creams are generally ineffective against UVA, and can be toxic and unstable. High SPF factor suncreams only refer to UVB blockage and protection and additionally total block creams can prevent the vital manufacture of Vitamin D in the body. They are also messy, need to be reapplied constantly and are the major contributor to death of the coral reefs throughout the world. Their chemical make up, often makes sunscreens a toxic cocktail, some of the ingredients of which cross the skin and enter the blood stream. Many are alcohol based allowing relatively easy transdermal absorption. Most are unstable and breakdown in the sun creating free radicals and reactive oxygen species. Even vitamin A (Retino) and vitamin A derivatives (vitamin A palmitate and retinyl palmitate) have been shown to be photo unstable. Most sunscreens contain Vitamin A which may become a pro oxidant, damaging the skin that it was designed to protect. Use a natural sunscreen and check the ingredients. Avoid titanium dioxide and micronized zinc oxide.
Systemic protection by phytonutrients.
Research has shown that certain nutrients can support the skins natural defence and minimise skin damage from the effects of UVA and UVB, reducing the risk of melanoma. This is primarily achieved through the nutrients powerful antioxidant capabilities. Grape seed extract, Green tea polyphenols and Curcumin (turmeric) have these antioxidant capabilities. These have all been incorporated into Sunlite along with other important antioxidants.
Vitamin C contributes to the protection of cells from oxidative stress and contributes to the regeneration of the reduced form of Vitamin E, which has also been included that offers protection of DNA, proteins and lipids in the cells from oxidative damage from the sun.
Vitamin K is included because it is needed to carry calcium (which has been absorbed from the diet) by Vitamin D being produced as a result of the sun exposure, out of the soft tissues to the bones. Build up of soft tissue calcium could be the cause of that “stiff feeling” from being in the sun for a long time.
Metabolics recommend that Sunlite is taken with a good Omega 3 or Krill Oil.
Omega 3 oils have been shown to reduce levels of Prostaglandins 2 ( PGE2), that are responsible for the inflammation in the skin in the skin NCBI.NIG.GOV .
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Made in our clean room facility, here in the UK.
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