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Preconception Formula (Pot of 150 capsules)


This product contains a proprietary blend of products which should be consumed in the diet before pregnancy.

Full product description

Suitable for vegetarians: Yes

Suitable for vegans: No

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What is Metabolics Preconception Formula?

Starting on the path to conceive and welcome a baby into your life can feel like a deeply meaningful and serious decision. At Metabolics, we fully appreciate the importance of this life-changing journey. That's why Metabolics Preconception Formula has been meticulously formulated, designed to support aspiring parents in their endeavour for optimal health before conception.

Preconception Formula is a result of extensive research and scientific expertise, combining essential vitamins, minerals, and antioxidants carefully selected to support normal reproductive health and overall well-being.

It is recommended that both potential parents take Preconception Formula at least one month prior to conception and preferably for three months.

Preconception nutrition and supplementation is important to maintain good nutritional status prior to conception to help minimise health risks to mothers and their babies.

It is also an important supplement that can be taken by the potential father as a good nutritional status is important for fertility.

New formula

We are always reevaluating our ingredients and formulas across our entire product range to ensure they are as effective and high quality as possible. As part of this activity, we recently (June 2024) identified improvements we could make to the Preconception Formula to ensure it better supports the nutritional needs of mothers to be and their future offspring. See our label updates page for more details.

The changes from our previous formulation include:

- Choline

We have sourced a new, branded version of choline bitartrate known as VitaCholineR choline bitartrate. This is a premium form of choline bitartrate.

Choline is an important nutrient during pregnancy, as maternal choline intake during pregnancy and lactation contributes to normal foetal and infant development, especially of the liver.

It is widely considered that people do not consume enough choline in the UK, which is explored in the article “Could we be overlooking a potential choline crisis in the United Kingdom?” by the British Medical Journal.

Whilst you should also source more choline from your diet, the Preconception Formula acts as a suitable nutritional support to prepare your body for pregnancy.

- Vitamin E

We have changed our source of vitamin E to a natural form of D Alpha Tocopherol. D Alpha Tocopherol is the form of Vitamin E required by the body and the bioavailability of α-tocopherol from α-tocopherol succinate is equivalent to that of free α-tocopherol. The daily recommended amount of Vitamin E as α- tocopherol is 12 mg. The Antenatal Formula offers 47% of your daily requirement.

A capsule now delivers 1.1mg where it used to deliver 0.76mg.

Other changes:

- Vitamin A has been increased from 200 µg to 224 µg per capsule.

- Vitamin D3 has been increased from 4.2 µg to 14.7 µg per capsule.

- Vitamin K2 has been increased from 13.3 µg to 14.6 µg per capsule.

- Vitamin C has been increased from 33 mg to 37 mg per capsule.

- Thiamin (Vitamin B1) has been increased from 0.83 mg to 0.9 mg per capsule.

- Riboflavin (Vitamin B2) has been increased from 0.83 mg to 0.9 mg per capsule.

- Niacin (Vitamin B3) has been increased from 3.3 mg to 3.7 mg per capsule.

- Vitamin B6 has been increased from 1.7 mg to 1.9 mg per capsule.

- Folate has been increased from 133 µg to 149 µg per capsule.

- Vitamin B12 has been increased from 17 µg  to 19 µg per capsule.

- Pantothenic Acid (Vitamin B5) has been increased from 1.7 mg to 1.9 mg per capsule.

- Calcium has been increased from 25 mg to 140 mg per capsule.

- Magnesium has been increased from 23 mg to 26 mg per capsule.

- Iron has been increased from 2.5 mg to 2.8 mg per capsule.

- Zinc has been increased from 2.5 mg to 2.8 mg per capsule.

- Copper has been increased from 0.19 mg to 0.22 mg per capsule.

- Manganese has been from increased from 0.33 mg to 0.37 mg per capsule.

- Selenium has been from increased 8.4 µg to 9.3 µg per capsule.

- Chromium has been from increased 5 µg to 5.6 µg per capsule.

- Molybdenum has been from increased 7.7 µg to 8.6 µg per capsule.

- Iodine has been increased from 25 mg to 28 mg per capsule.

- Choline has been increased from 19  mg to 21 mg per capsule.

- Inositol has been increased from 4.2 mg  to 4.7 mg per capsule.

- Lutein has been increased from 0.8 mg to 0.9 mg per capsule.

- Zeaxanthin has been increased from 17 µg to 18.5 5 µg per capsule.

- Plant squalene has been removed

- Phytosterols has been removed

While there may be increases per capsule, in some cases this is a decrease per total dose; the dosage has now gone from 6 capsules to 5 capsules. Increases in certain ingredients have been to better align with recommendations for pregnancy. Where ingredients have been reduced it is where the previous value was not necessary and to make room for increases in more important ingredients.

What is Metabolics Preconception Formula good for?

Metabolics Preconception Formula consists of a balance of nutrients that support normal reproductive health. Such nutrients include:


If there is inadequate folate in the diet, then anaemia or neural tube defects of the spine (spina bifida) or brain (anencephaly) may occur. It is difficult to obtain enough levels of folate in the diet, so recommendations are for women of child-bearing age to take 400 micrograms of folate daily by supplementation one month before conception and up to three months after. Supplemental folate, or folic acid, intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing foetus.

Prenatal folate is important for early child development.


Maternal choline intake during pregnancy and lactation contributes to normal liver function of the foetus and exclusively breastfed infants.

According to this 2023 article “Choline and contribution to normal liver function of the foetus and exclusively breastfed infants” published by the EFSA, ‘there is a gap in supply of choline during pregnancy and lactation of ~ 100 mg/day that needs to be achieved via additional intake, through the natural diet or a supplemental source of choline. These amounts are also aligned with other claims based on essential nutrients, where the claim may be used only for food which is at least a source of choline. Such minimum amounts could be derived with 15% from the adequate intake levels of choline corresponding to 72 and 78 mg/day choline for pregnancy and lactation, respectively.’

Who is Metabolics Preconception Formula for?


A study titled “Micronutrients intake is associated with improved sperm DNA quality in older men” showed that men with higher levels of certain micronutrients might produce sperm with less DNA damage, especially in older men. These nutrients included Vitamin C, E, Beta-carotene, Zinc and Folate.

Zinc in particular, contributes to normal fertility and reproduction, normal DNA synthesis, and the maintenance of normal testosterone levels in the blood. This mineral is generally associated with the normal functions of the male reproductive system, therefore it is extremely important to maintain good zinc status. Deficiency in zinc is associated with low testosterone levels, poor sperm quality and an increased risk of male infertility, as highlighted in the study “Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.”.

Selenium is alos included in Preconception Formula as it contributes to normal spermatogenesis and protects cells from oxidative stress.

Selenium forms part of the selenoenzymes and these protect sperm form damage and mutation. They make up part of the cell structure and the protein substances in the sperm tail. Combining Selenium with vitamin E is reported to have beneficial and protective effects on sperm motility, as suggested in the study “Selenium–vitamin E supplementation in infertile men: effects on semen parameters and pregnancy rate”.

Men should take at least three months, but preferably six months, of Metabolics Preconception Formula, as this gives two full cycles of sperm production.



A review of studies of micronutrient supplements on female fertility in Current Opinion of Obstetric Gynaecology on April 6 2013 summarised that “Apart from lowering the malformation risk by periconceptual supplementation of folic acid, substitution with different micronutrients particularly folic acid, Vitamins B6, C, D, E, Iodine, Selenium, Iron and DHA.

There are certain nutrients that are particularly important to build up prior to conception.  Requirements for folic acid, calcium, iron, and zinc, Vitamin D, Vitamin C and Vitamin B increase substantially during pregnancy so it is essential to have an adequate pool of these.

Why use Metabolics Preconception Formula

It is particularly important to use a high quality nutritional supplement preconceptually that does not contain pesticide or heavy metal residues and contains nutrient forms that are particularly bioavailable. As this is a daily supplement, it is also important that it contains vitamins at levels safe for mother and baby. Metabolics is particularly careful to source very high quality, bioavailable ingredients.

With a commitment to quality and safety, our supplement is manufactured under strict regulations, using premium ingredients that meet the highest industry standards. We aim to provide you with the confidence and reassurance you need as you take this momentous step towards starting a family.

At Metabolics we are renowned for our commitment to delivering high-quality supplements. Our liquid products stand out due to our meticulous manufacturing process. These liquid supplements are carefully crafted using pure water, ensuring the highest standards of purity and cleanliness. The water used in our production undergoes a rigorous purification process, reaching 18.2 megohms (MΩ). This ultra-pure water ensures that the final liquid products are free from impurities, contaminants, and unwanted substances, guaranteeing exceptional quality and efficacy.

This product is suitable for vegetarian diets.

Food supplements made to GMP standards.

Made in our clean room facility, here in the UK.

ISO accredited ISO:9001 and ISO:14001 accredited.


Salama Kefentse-Francis | Posted 10 months ago | Read full review
Trusted Customer | Posted 10 months ago | Read full review
"seeems ok - will know after use"
Trusted Customer | Posted 1 year ago | Read full review
"Good quality and very helpful"
Trusted Customer | Posted 3 years ago | Read full review
"Great product, made me feel secure in knowing I was as prepared as possible for pregnancy and for a healthy baby"
Trusted Customer | Posted 3 years ago | Read full review
5 capsule dose contains:
%NRV* per serving
Vitamin A
1120 µg
23 %
(as beta Carotene)
Vitamin D3
24µg (960 IU)
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Magnesium Citrate, Calcium Citrate, Hydroxypropyl Methylcellulose (capsule), VitaCholine®Choline Bitartrate, Astaxanthin Powder, Ascorbic Acid, Iron Pyrophosphate, Zinc Bisglycinate, Lutein Powder, Menaquinone 7, Inositol, Niacinamide, Pyridoxal 5 Phosphate, Beta Carotene powder, Calcium Pantothenate, Selenium Methionine on Divcalcium Phosphate, Cholecalciferol, Manganese Citrate, Riboflavin 5 Phosphate, Thiamine HCl, Copper Citrate, Calcium- L-Methyl Folate, Zeaxanthin powder, Chromium Picolinate, Potassium Iodide, Sodium Molybdate, Methylcobalamin, Biotin. VitaCholine® is a registered trademark of Balchem Corp.

No Gluten Containing IngredientsNo Gluten Containing Ingredients
No Nut Containing IngredientsNo Nut Containing Ingredients
Take 3 capsules in the morning and 2 capsules in the afternoon with food. The stated recommended dose can be changed as directed by your healthcare practitioner. Do not exceed this recommended dose. Consume within 3 months of opening.
Not suitable for vegans. This product should not be used as a substitute for a varied diet.
Store in a cool, dry place out of reach of children.
Serving size: 1 capsule