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Metabolics Vitamin B12 (Methylcobalamin)
What Is Metabolics Vitamin B12 (Methylcobalamin)?
Vitamin B12 is one of the 13 essential vitamins needed by the human body to support life and health. It stands out among the vitamins as it cannot be obtained from plants or through sunlight. Instead, it is synthesised by bacteria in the gut of animals and absorbed in the small intestine.
Dietary sources of B12 include meat, fish, and dairy products, but even individuals with animal-based diets may struggle to absorb sufficient B12 due to the complex multi-step absorption pathway.
Vitamin B12 is first released from food in the stomach with the help of acid and enzymes. It binds to a carrier protein (haptocorrin) and is later freed in the small intestine. B12 then attaches to Intrinsic Factor, which helps it travel to the ileum for absorption into the bloodstream. Once absorbed, it is delivered to body tissues by Transcobalamin II. Without enough stomach acid, Intrinsic Factor, or healthy intestines, B12 absorption can be reduced.
Vitamin B12 deficiency can affect anyone at any age, but certain groups are at higher risk. These include vegans and vegetarians, adults over 60, individuals with eating disorders such as anorexia or bulimia, and those taking medications like antacids or diabetes treatments that interfere with B12 absorption. People with a history of alcoholism, anaemia, or gastrointestinal conditions such as Crohn’s disease and IBS are also more vulnerable. Autoimmune conditions like type 1 diabetes, Addison’s disease, and SLE can increase risk, as can a family history of pernicious anaemia. Women with infertility or recurrent miscarriage, as well as infants born to or breastfed by deficient mothers, should also be aware of their B12 status.
What is Methylcobalamin?
Methylcobalamin is a bioactive, coenzyme form of vitamin B12. It consists of a cobalt ion (Co³⁺) held within a corrin ring structure, directly attached to a methyl group (-CH₃). As an active form, it does not require conversion in the body and is essential for homocysteine methylation and the maintenance of healthy nerve cells.
What Is Methylation and Why Is It Important?
Methylation is a crucial biochemical process in which a methyl group (CH₃) is added to molecules within the body. It affects many essential functions, including gene expression, detoxification, neurotransmitter production, hormone regulation, and energy metabolism.
Vitamin B12 is critical to this process, as it helps convert homocysteine into methionine — a precursor to S-adenosylmethionine (SAMe), which supports emotional balance, detox pathways, and healthy cellular function. Because methylcobalamin is already in a methylated, active form, it can be directly used by the body. This is especially valuable for individuals with MTHFR gene variants, who may have difficulty generating sufficient methyl groups.
What Is Metabolics Vitamin B12 (Methylcobalamin) For?
This product offers high strength vitamin B12 in its active form, methylcobalamin, which is directly used by the body without the need for conversion.
Key Benefits of Vitamin B12
✔ Contributes to Normal Energy-Yielding Metabolism
Vitamin B12 supports the conversion of food into energy by acting as a coenzyme in the breakdown of fatty acids and amino acids, helping sustain vitality throughout the day.
✔ Supports the Normal Function of the Nervous System
Essential for the maintenance of the myelin sheath that protects nerve fibres, B12 ensures proper nerve conduction and coordination. Deficiency can lead to neurological symptoms such as numbness, tingling, and cognitive decline.
✔ Contributes to Normal Homocysteine Metabolism
Methylcobalamin is involved in the conversion of homocysteine into methionine. This helps maintain cardiovascular health and reduce homocysteine levels, which are associated with heart disease risk.
✔ Supports Normal Psychological Function
B12 contributes to the synthesis of neurotransmitters and supports brain function, memory, and emotional balance. Deficiency may manifest as irritability, low mood, or even cognitive impairment.
✔ Contributes to Normal Red Blood Cell Formation
Essential for DNA synthesis, vitamin B12 supports the production of healthy red blood cells. A deficiency can lead to megaloblastic anaemia, characterised by fatigue and weakness.
✔ Supports the Normal Function of the Immune System
By promoting the integrity of DNA synthesis and cell division, B12 plays a role in supporting immune cell development and resilience.
✔ Has a Role in the Process of Cell Division
B12 is crucial for cell replication, especially in tissues with high turnover, such as the lining of the gut and the production of immune and blood cells.
✔ Contributes to the Reduction of Tiredness and Fatigue
Because of its involvement in red blood cell formation and energy production, B12 can help reduce fatigue, particularly in individuals with low micronutrient status.
Signs of Vitamin B12 Deficiency May Include:
• Fatigue and low energy
• Mood changes such as irritability, depression, or confusion
• Numbness or tingling in extremities
• Pale skin and breathlessness (linked to anaemia)
• Digestive discomfort, bloating, constipation
• Memory loss or neurological decline
• Poor wound healing and susceptibility to infection
• Vitiligo, premature greying, or skin changes
Who Is Metabolics Vitamin B12 (Methylcobalamin) For?
This supplement is ideal for individuals who:
✔ Follow vegan or vegetarian diets
✔ Have increased nutritional demands due to lifestyle, age, or health status
✔ Show signs of deficiency such as fatigue, tingling, or mood disturbances
✔ Require a bioactive, high-quality, methylated form of B12
Why Choose Metabolics Vitamin B12 (Methylcobalamin)?
🔹 Scientifically Validated – Supported by UK & EFSA-authorised health claims
🔹 Bioavailable Active Form – Methylcobalamin is directly used by the body
🔹 Clean Formulation – Free from unnecessary additives
🔹 Third-Party Tested – Independently verified for quality and purity
✅ Order Metabolics Vitamin B12 (Methylcobalamin) Today!
Support your energy, mental clarity, and neurological function with this high-quality supplement. Shop now and prioritise your health.
Supplement Facts
Each capsule contains:
%NRV*
Vitamin B12
1000 ug
40000 %
† Nutrient Reference Value (NRV*) not established
Ingredients
Cellulose, Hydroxypropyl Methylcellulose (capsule), Methylcobalamin.
Directions / Dosage

Warning
Storage
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