Acetyl L. Carnitine and Alpha Lipoic Acid (Pot of 60 capsules)

A proprietary blend of the amino acid Acetyl-L Carnitine and antioxidant, Alpha Lipoic Acid.

 
£26.48
 
 
Suitable For
Vegetarian Vegetarian
Vegan Vegan
No Gluten Containing Ingredients No Gluten Containing Ingredients
No Nut Containing Ingredients No Nut Containing Ingredients

Acetyl L. Carnitine and Alpha Lipoic Acid

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Acetyl-L Carnitine is a form of carnitine, an amino acid found naturally in every cell in the body and is an antioxidant. Amino acids are building blocks that make proteins .It has been shown to reduce damage to the energy producing mitochondria. Carnitine plays a role in transporting fatty acids into the mitochondria.

Alpha lipoic acid is also an antioxidant made in the body and found in every cell. It can pass easily to the brain and is both water and fat-soluble Liu and colleagues tested aged rats with oral acetyl-L-carnitine and lipoic acid to see if the supplementation reduced mitochondrial aging in the brain [1] A group from Oregon State University reviewed the literature and suggested that together, acetyl-L-carnitine and lipoic acid were able to protect the heart from aging as well as reverse age-related changes [2]. Importantly, they also stated that they are most effective when used together [2]. Chiecho and colleagues showed that acetyl-L-carnitine in rats altered the DNA in the spinal cord cells by increasing the production of mGlu2 receptors, an important receptor for pain relief [3].

Please note: The European Food Safety Authority is examining the potential for a link between the consumption of alpha lipoic acid, and the development of insulin autoimmune disease in individuals with certain genetic polymorphisms. Whilst the EFSA works to establish whether or not a link exists, anyone who thinks they could be at risk of insulin autoimmune disease should seek professional medical advice before purchasing this product

References
(1) Liu, J. Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-?-lipoic acid. Proc. Natl. Acad. Sci. USA 2002;99:1876-81.
(2) Hagen, T.M. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. PNAS. 2001 99 (4) 1870-1875 Hagen, T.M. Mitochondrial decay in the aging rat heart: Evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. Ann. NY Acad. Sci. 2002;959:491-507.
(3) Chiechio, S. l-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. Mol Pharmacol(2002) 61: 989-996.

Quality Assured:

GMP Supplements Made to GMP standards.

Made in the UK Made in our clean room facility, here in the UK.

ISO accredited ISO:9001 and ISO:14001 accredited.

This product is suitable for vegetarians and vegans.

Supplement Facts

Each capsule contains:

%NRV*

Acetyl L Carnitine HCl

250 mg

Alpha Lipoic Acid

250 mg

† Nutrient Reference Value (NRV*) not established

Ingredients

Acetyl L Carnitine HCl, Alpha Lipoic Acid, Hydroxypropyl Methylcellulose (capsule).

Directions / Dosage
Capsules
Recommended dose 1 capsule per day with food. The stated recommended dose can be changed as directed by your healthcare practitioner. Do not exceed this recommended dose. Consume within 3 months of opening.
Warning
If pregnant or breast feeding, consult your health care practitioner before using. This product should not be used as a substitute for a varied diet.
Storage
Store in a cool, dry place out of reach of children.
Product Type
Serving size: 1 capsule