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Vitamin B2 (Riboflavin 5 Phosphate) (Pot of 60 capsules)

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Vitamin B2 (Riboflavin)

Both FAD and FADH2 are manufactured in the cells once Vitamin B2 (Riboflavin) reaches the small intestine, so anyone on a good diet will be able to make FAD and FADH2 themselves so we recommend Riboflavin 5 Phosphate.

If their diet is poor, we recommend that a multivitamin (nutrimax) be taken in conjunction with the Riboflavin 5 Phosphate to ensure all co-factors are present for absorption.

Vitamin B2 is one of the 8 water-soluble B vitamins, meaning the body cannot store them. Riboflavin is destroyed by light and heat and in an alkaline medium. It is absorbed in the upper part of the small intestine, is increased with food and delayed on an empty stomach. There is decreased absorption in cases of gall bladder or liver disease and are associated with decreased dietary intake of meat and dairy products.

Folate and Vitamin B6 (Pyridoxine) need R5P for conversion to their bioavailable forms, Methyltetrahydrofolate and Pyridoxal 5 Phosphate respectively. The active forms (the forms in which the body uses them) of Riboflavin are synthesised in the mitochondria, forming Riboflavin 5 Phosphate which is then converted further to Flavine Adenine Dinucleotide (FAD) Metabolics Vitamin B2 is in its bioavailable form Riboflavin 5 phosphate. What does Vitamin B2 do?

  • It contributes to normal energy yielding metabolism - Vitamin B2 is required in its coenzyme form (FAD) for participation in the Citric Acid cycle to produce energy.
  • It contributes to normal functioning of the nervous system - Again in its Coenzyme form, FAD , Vitamin B2 is needed for the monoamine oxidase enzyme, which functions in the metabolism of neurotransmitters ( brain chemicals ) for normal functioning of the nervous system.
  • It contributes to the maintenance of normal red blood cells - Vitamin B2 improves iron absorption and riboflavin deficiency induces anaemia , where there are immature red blood cells.
  • It contributes to the maintenance of normal skin and mucous membranes–both acute and chronic deficiencies result in mucocutaneous lesions that disappear after adequate doses of B2 are given.
  • It contributes to the maintenance of normal vision- Riboflavin deficiency is associated with decreased activity of the enzyme glutathione reductase, the enzyme responsible for the production of glutathione. Reduced glutathione protects the lens of the eye from oxidative damage and is decreased in cataracts. Riboflavin deficiency can cause conjunctivitis with vascularisation of the cornea and opacity of the lens (cataracts).
  • It contributes to the normal metabolism of iron. Iron metabolism is impaired in riboflavin deficiency. The utilisation of iron reserves from the intracellular protein ferritin requires riboflavin. Riboflavin is required for haemoglobin synthesis.
  • It contributes to the protection of cells from oxidative stress. Vitamin B2 participates in many reactions where the cofactors P-5-P and FAD act as electron carriers, protecting the DNA, proteins and lipids from oxidative damage.
  • It contributes to the reduction of tiredness and fatigue As Vitamin B2 is involved in manufacturing energy adequate doses of B2 contribute to normal metabolism resulting in energy.

    Deficiency of Vitamin B2 Clinical signs and symptoms may appear 3-8 months after deficiency. These include sores at the corners of the mouth, sore tongue, dermatitis numbness of the hands or decreased sensitivity to touch, temperature and vibration and visual changes. There may be the tiredness and fatigue associated with anaemia. Alcohol decreases the bioavailability and absorption of riboflavin.

  • Vitamin B2 (Riboflavin 5 Phosphate)

    Recent customer reviews

    1. I was recommended this product for my son by my kinesiologist. Several years ago,...
      Shilpa | (13/05/2017)
    2. I was advised to take this product together with zinc sulphate when I was confusingly...
      Jet | (12/07/2015)
    View all customer reviews

    Vitamins B2 R-5-P Food Supplement 60 Capsules


    Cellulose, Riboflavin 5 Phosphate, Hydroxypropyl Methylcellulose (capsule)

    Directions: Recommended dose 1 capsule per day with food*. Do not exceed this recommended dose. Consume within 3 months of opening.

    Warning: If pregnant or breast feeding, consult your health care practitioner before using. This product should not be used as a substitute for a varied diet.

    Storage: Store in a cool, dry place out of reach of children.                                                                       


    *The stated recommended dose can be changed as directed by your healthcare practitioner.


    Product information

    Serving Size: 1 capsule

    Each capsule contains                     %NRV*


    Riboflavin (Vitamin B2)                  47.5 mg                  3393 %







    † Nutrient Reference Value (NRV*) not established

    Customer Reviews

    1. Fabulous product, Review by Shilpa
      Speed of delivery

      I was recommended this product for my son by my kinesiologist. Several years ago, my son (who was about 4 or 5 at the time) started having stomach, back and joint pain and would wake up all through the night - which also left me exhausted. He also wasn't eating as he usually would, due to stomach pain. This is a child who had a fabulous appetite, was never fussy with food, slept soundly through the night and never complained of pain, so it was extremely odd and frustrating as well.

      The kinesiologist I used, was different to other kinesiologists I have been to. She diagnosed that he was unable to convert Riboflavin to its next form and recommended this product (which used to be called FADH2).

      It worked amazingly. Within the week, the body aches and pains had vanished, he was sleeping well and he was eating properly. She told me that during a growth spurt he may need 1 extra capsule, which I used. I don't need to use it as much as I used to, but I still do use it with him.

      I love the quality of this product and they send it to you extremely fast as well!


      (Posted on 13/05/2017)

    2. Very effective, Review by Jet
      Speed of delivery

      I was advised to take this product together with zinc sulphate when I was confusingly diagnosed as being hypothyroid. The kineseologist I saw recognised that I could be suffering from mercury filling toxicity from old leaky fillings. He recommended the Metabolics company - and I thought - o.k. - lots of practitioners have their favourite companies that they get a discount from but the supplements aren't necessarily effective. I wasn't sure that most brands of supplements were effective.

      However as a therapist myself and someone who has a body that is sensitive to the effects of substances I put into it - I began to feel its good effects shortly after taking the product and within a few days even what was diagnosed as hypothyroidism began to change. I feel this company has high standards of processing their supplements and I'm surprised that no one has written reviews in the review area of these pages.

      Best wishes to you Metabolics,

      (Posted on 12/07/2015)

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    © Metabolics ltd, 2019. All rights reserved. Metabolics is a limited company registered in England and Wales 2844683. VAT registration number GB 249 9873 34.

    Metabolics ltd is registered with the U.S Food and Drug Administration pursuant to the Federal Food Drug and Cosmetic Act, as amended by the Bioterrorism Act of 2002 and the FDA Food Safety Modernization Act. 

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