Suitable for vegetarians: Yes
Suitable for vegans: No
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Metabolics Vitamin A and Vitamin D Drops are a blend of Vitamin A (retinyl palmitate) and vitamin D (cholecalciferol) in avocado oil. The avocado oil is obtained by pressing the dehydrated sliced flesh of the avocado pear. It is non-GMO and non-irradiated, mild in taste and can easily be added to food.
Taking vitamin A and vitamin D is important for various aspects of health and wellbeing. Both vitamins play distinct roles in the body and contribute to different physiological functions.
Vitamin A is essential for vision, growth differentiation and proliferation of a wide range of epithelial tissues, bone growth, and reproduction.
Vitamin A is essential for maintaining the health of epithelial cells, meaning the cells on the surface of the body. It does this through the action of retinoic acid, which is a metabolite of vitamin A and plays a crucial role in regulating the expression of various genes. These genes encode for essential components such as structural proteins, enzymes, extracellular matrix proteins, as well as proteins and receptors responsible for binding and transporting retinol, as discussed in the paper “Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc” by the Institute of Medicine (US).
A deficiency in vitamin A can lead to widespread effects on the body. These effects include skin dryness characterised by excessive keratin production in hair follicles, a reduction in mucus-secreting goblet cells in the respiratory tract and trachea, and a generalised transformation of epithelial cells where they become flatter (referred to as squamous metaplasia). In some cases, this transformation might also involve keratinization, as referred to in the chapter “Vitamin A | Physiology” by A.C. Ross.
Our eyes need something called 11-cis-retinaldehyde (or retinal) to help turn light into signals that our brain can understand. This is really important for our vision. Inside special cells in our eyes called rod cells, retinal combines with opsin to create rhodopsin, which is a special pigment for our vision. When light enters our eyes and hits rhodopsin, it starts a process that changes 11-cis-retinal into all-trans-retinal. This change sends signals to our brain so we can see things. Maintaining an adequate level of vitamin A in the retina is essential. In situations of low light, if vitamin A levels are insufficient, the functioning of rod cells is compromised, resulting in an abnormality in adjusting to darkness, commonly known as night blindness, this is also highlighted by the Institute of Medicine.
In addition to this, Vitamin A supplied through tear fluid plays a vital role in supporting the health of the cornea. This is integral for cell differentiation and upholding the structural integrity of the cornea. When there's a deficiency of vitamin A, mucus production by the goblet cells in the conjunctival membranes diminishes, leading to dryness of the cornea (xerosis). Additionally, the formation of Bitôt spots, which is accumulated cellular debris, becomes possible. This usually occurs in the outer quadrant of the eyes, as suggested in the research by A.C. Ross in the chapter Vitamin A and Carotenoids in Modern Nutrition in Health and Disease.
Vitamin D has been shown to have numerous biochemical functions that impact upon the capacity of the immune system to function optimally. Vitamin D helps regulate the function of various immune cells, including T cells and B cells. These cells are responsible for identifying and targeting pathogens (such as bacteria and viruses) and abnormal cells. Proper regulation of these immune cells is essential for an effective immune response. Vitamin D is involved in the differentiation of monocytes and macrophages, two types of immune cells that are essential for engulfing and eliminating pathogens. Proper differentiation ensures these cells function optimally. Vitamin D also supports the innate immune response, the body's initial defence against infections. It helps activate innate immune cells to quickly respond to invading pathogens.
Vitamin D is well-known for its role in calcium absorption and bone health. It helps regulate calcium and phosphate levels in the body, which are essential for maintaining strong bones.
The UK Department of Health recommends that all children from six months to five years are given a daily supplement that contains vitamins A, C and D, as stated by the NHS in its Vitamins for Children and baby vitamins advice. Babies from birth until their first birthday who are breastfed should be given a daily supplement containing 8.5 to 10 micrograms of vitamin D and children aged 1 to 4 years old should be given a daily supplement containing 10 micrograms of vitamin D. Babies who are given more than 500ml infant formula a day should not be given a food supplement as infant formula is fortified with vitamins and minerals.
It is simple to administer with just 4 drops taken daily.
Vitamin A and D drops serve a variety of health-related purposes, particularly when individuals might not be acquiring sufficient amounts of these vitamins through their diet or exposure to sunlight.
The NHS recommends a daily intake of 10ug of vitamin D for adults all year-round.
Vitamin D is naturally present in only a handful of foods, such as eggs and oily fish. Although it's also fortified in certain foods, solely relying on dietary sources can make it challenging to obtain adequate vitamin D levels.
Notably, awareness of Vitamin D deficiency has markedly risen within the UK population in recent times. This has led to a surge in published articles addressing the topic.
Vitamin A health benefits:
Vitamin D health benefits:
A very small amount (<0.5%) of carrier oils from the individual vitamins are present so we declare those on the label. Vitamin A is formulated in sunflower oil. Vitamin D is formulated in MCT (medium chain triglycerides which is sourced from coconut).
Food supplements made to GMP standards.
Made in our clean room facility, here in the UK.
ISO accredited ISO:9001 and ISO:14001 accredited.
Avocado Oil, Retinyl Palmitate (Sunflower Oil), Cholecalciferol (Medium Chain Triglycerides), Antioxidant (DL-Alpha-Tocopherol).
Vegetarian
No Gluten Containing Ingredients
No Nut Containing Ingredients
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