Alison regularly reviews the latest published research whilst developing new products. These new blog posts aim to highlight some of those recent publications that you may find interesting, and deliver them in small bitesize chunks. This post highlights pregnancy, contaminated fish oils and the link between B vitamins and fish oils.Read More
Vitamin B Complex Liquid
Metabolics is proud to announce their new Vitamin B Complex liquid. This is unparalleled in its composition, supplying the highest quality B vitamins all in the most bioavailable, coenzyme forms. This means that they are in forms that the body can absorb readily and be directly utilised by the body without requiring conversion in the enterocytes or the liver before being released into the general circulation.
Most nutritional supplement companies’ use the cheaper forms of vitamins, in particular the B vitamins that need to be converted to their active coenzymes.Read More
Metabolics are delighted to announce we will be hosting a second Women’s Health Seminar in London at the wonderful 110 Rochester Row.
The seminar will once again feature Dr Emma Derbyshire, who provided a range of superb presentations in our previous womens health seminar.Read More
Last week saw the end of the “sell through” period for the Traditional Herbal Medicinal Products Directive (THMPD); as such we have withdrawn any of our products that would be considered unlicensed herbal medicines under the scheme.Read More
Iron is incredibly important mineral and is found in every living cell so I thought I'd write a short post on the importance of iron as mineral as well as the signs of being deficient in Iron can lead to.Read More
After a long period of working with the US FDA, we have finally achieved official notification of compliance.
This means we are now able to resume distribution of all products within the United States with the exception of our probiotics and Bio Silver. We send every batch of our supplements away for external laboratory testing to verify the quality of the product. Unfortunately, the cost of the testing on probiotic products is cost prohibitive at present. However, this is something we are working on and we will notify our American customers once we have achieved a resolution.Read More
Metabolics are proud to announce we will be sponsoring the up and coming “Vitamin D and Human Health: From the Gamete to the Grave” conference presented by the Vitamin D Council. This academic meeting will be held at the Queen Mary, University of London over a period of three days from the 23rd to the 26th of April 2014.Read More
Vitamin A is essential for all mammals. Preformed vitamin A is a group of fat-soluble compounds of animal origin called retinoid. It is found in eggs, milk products and animal liver. In countries low in foods derived from animals, carotenoids from vegetables need to supply the requirements for Vitamin A. In Asia and in Africa this can be 80% of the dietary intake whilst in the Western diet, as much as 40% of dietary intake.Read More
Manufacturing facilities and Procedures
Most people do not consider where their supplements come from, or how they are made. Generally people believe that their supplements are made in research laboratories, by people in white coats, manufactured in pharmaceutical grade facilities.
The truth is that in the UK anybody can set up as a nutritional supplement manufacturer mixing and formulating in their kitchen.
In the United States, Good Manufacturing Process (GMP) regulations and requirements came into effect in June 2010, extending those requirements to any foreign (UK) facility that supplies to the States. This means that regardless of what country you are based in, if you supply to the US, you need to comply with these regulations.Read More
Alzheimer’s disease is a progressive degeneration of the nervous system where the death of brain cells over time causes memory loss and cognitive decline (dementia).
There are 2 common forms of dementia, Alzheimer’s disease which according to the Alzheimer’s society accounts for 60-80% cases of dementia and vascular dementia which is caused by stroke.
Alzheimer’s like any dementia is the result of brain cell death where there are progressively fewer nerve cells (neurons) and connections (synapses) and the total brain size shrinks.Read More
Osteoporosis is decreased bone density, which means it is porous and weakened at risk of fracture. It is common in postmenopausal women because Oestrogen regulates osteoclasts removal of dead demineralised bone and progesterone is required by osteoblasts to build new bone, so decreased oestrogen means increased bone resorption, and decreased progesterone means less bone building.Read More
We all know about Genetics, understanding that we are all born with genes composed of DNA and made up of a sequence of nucleotide bases in a particular order that we inherit from our parents. We are all familiar with the concept that our genes are responsible for our eye colour, hair colour and predisposition towards disease states such as breast or prostate cancer.
Scientists once believed that genes were fixed from the moment of conception but research since 2004 has demonstrated that genes can be turned on or off and are subject to environmental influences such as nutrition, stress and emotions.
Epigenetics literally means “On Top of the Gene” ,so the DNA that you have inherited remains in the same sequence but these other factors such as nutrition and the chemicals produced by stress and emotions determine whether that gene that you have inherited is expressed and the disease manifest.Read More
What Is Memory?
Both learning and memory are a result of complex biochemical reactions.
The main processes involved in memory are encoding, storing and retrieving of information.
When a new memory is created the information is encoded and then stored in the brain. When the memory is recalled, the retrieval process brings that stored information back into conscious awareness. The capacity of the brain to change with learning is known as plasticity. Changes in Long Term potentiation ( increased action potential along a nerve) and changes in strength of synapse connections may last weeks or months. 2 types of receptor allow the influx of calcium ( regulated by magnesium) resulting in a strengthening of the synapse.
In 1968, Atkinson and Shiffrin proposed the stage model of memory. This theory involves the 3 different stages of memory, sensory memory, short-term memory and long-term memory.Read More
The human body absorbs approximately 400kg zinc over the average 70-year lifespan and at any one time there should be 2-4 gm zinc in the body. It is the second most abundant mineral ion ( Magnesium is the first) in the body and is the only metal that appears in all enzyme classes The body absorbs 20-40% of zinc in food, zinc from animal foods being more readily absorbed (twice as much ) than zinc from plant foods. Zinc is also more readily absorbed with a protein meal and although the body cannot store zinc and it is needed every day in small amounts (50mg or less), it may be held in metallothionine reserves and transferred in metal transporter proteins. Metallothionines in the intestinal cells are capable of adjusting the absorption of zinc by 15-40%. Thus control of cellular zinc homeostasis is maintained by zinc proteins and zinc binding metallothioneines.Zinc is needed for over 300 enzymes in the body and makes up part of 3000 different proteins in the body. Muscles (60%)and bones (30%) contain 90% of the body’s zinc. High concentrations of zinc are found in the prostate gland and semen and the choroid of the eye.Read More
I've decided to produce a short blog post this week on the best forms of B12 found within supplements. There are 4 supplemental forms of Vitamin B12 which can be found below.
Hydroxycobalamin: Is not a form normally found in the human body, primarily produced by bacteria but can be converted in the body to useable, coenzyme forms of B12, methylcobalamin and adenysylcobalamin, the only forms able to cross the blood brain barrier. Interestingly, Hydroxycobalamin attaches itself to cyanide and is therefore used for smoke inhalation victims If glutathione is low the conversion from hydroxycobalamin will be blocked and methylcobalamin would be the preferred form of B12Read More
How Does The Body Produce Energy? | The Body Has 4 Methods To Create ATP (Adenosine Triphosphate) A Unit Of Energy.
Energy is supplied to all cells in the body including muscle cells by ATP generated from carbohydrates, fats and proteins .The unit of energy in the cells is called ATP (Adenosine Triphosphate)
The body has 4 methods to create ATP, they vary by speed and whether they burn oxygen or not.Read More
OptimEyes formula has been designed to provide nutrients that may provide protection against the development or advancement of the common conditions that affect the eyes. In order to better understand the different conditions of the eye, and how certain nutrients may help, I will briefly review the anatomy of the eye.
Light passes through the cornea, at the front of the eye, through the pupil, (the space at the centre of the coloured iris), through the lens to hit the tissue at the back of the eye, the retina and then a message is sent through the optic nerve to the brain to tell the brain what it is looking at. The lens is suspended and held in position by zonules, which are small fibres that pull on the ciliary muscles. When we naturally focus (or accommodate) the ciliary muscles contract and pull on the zonules which then pull on the edges of the lens and change its shape.Read More
Calcium is the most abundant mineral in the body, 99% of calcium in the body is in the teeth and bones. The other 1% is found in the blood and extracellular fluid and it is vital to maintain these calcium levels t a particular concentration range for normal physiological functions.
In order for calcium to be absorbed from the gut and utilised correctly, adequate Vitamins D and K, Magnesium and Phosphorus are necessary (See Metabolic Vitamin D, K and Magnesium)
Calcium cannot be manufactured by the body and must be obtained from food. Food sources of Calcium are milk and cheese products, some nuts and dark green leafy vegetablesRead More
Following much speculation, the Communication Workers Union has announced that Royal Mail have voted in favour of strike action.
Strike action was confirmed yesterday 16th October with a 24-hour strike taking place on Monday 4th November. The union will be in talks with Royal Mail over the next two weeks to try to prevent the strike, but is also considering further strike action.
Any customers placing an order online or over the phone on Saturday 2nd , Sunday 3rd and Monday 4th of November will experience a slight delay in receiving their orders through the post.Read More
I have created what I would consider to be a definitive guide to magnesium and magnesium supplements. I hope you find this post informative and interesting.
Magnesium is the second most abundant mineral inside our cells and the second most common deficiency, next to Vitamin D.
Recently scientists have discovered the ‘Magnesome’, a protein encoding gene incorporating Magnesium, suggesting that the levels of Magnesium in the body may epigenetically alter the expression and behaviour of some of the proteins in our bodies, so altering the expression of health or disease of tissues.Read More
Following on from our women’s health seminar I thought I would write a blog post documenting some of the interesting research that originally lead me to investigate whether or not it is possible to positively support menopause through diet and nutrition.Read More
The skin is the largest organ in the body, making up 15% of total body weight. It protects the body from bacteria, viruses, funguses, parasites, chemicals and the sun. It is important as a sensory organ, for temperature regulation, preventing water loss and storing water and fat.
The skin is made up of 3 layers, the epidermis, the dermis and the subcutis (subcutaneous fat layer). The epidermis contains melanocytes that are cells that produce skin pigment known as melanin. The dermis is the middle layer of skin containing blood and lymph vessels, hair follicles and sweat glands, nerves, collagen and special cells called fibroblasts, which make collagen. The subcutis is a network of collagen and fat cells conferring protection, strength and insulation against heat loss.Read More
The government has now publicly recommended that many people should be taking a supplement containing Vitamin D. This has come as quite a refreshing surprise for several reasons.
It is currently extremely difficult to tell consumers anything about supplements thanks to restrictions from the EFSA. Regardless of what the wider scientific community believes the effects of certain nutrients are, if the EFSA don’t agree then you’re not allowed to say it.
This means that we are often not allowed to tell consumers why they would take a specific supplement, or even provide them with the information they would need to make an informed decision themselves.Read More
In this blog post I’ll be looking at some of the research that has been conducted to evaluate whether osteoporosis can be supported through good diet or nutritional supplements.
First of all though it is a little easier to understand the research with a bit of background knowledge:Bone is a dynamic tissue being continually broken down and rebuilt in a process known as “remodelling”. Cells called osteoclasts, made in bone marrow break down and reabsorb bone tissue liberating calcium and other minerals stored in the bone matrix. Bone stores calcium phosphate and growth factors.Read More
I wanted to thank everyone that joined us on Saturday 3rd of November at the Royal College of Physicians for the great talks that were delivered by our speakers.
It was certainly one of the best CPD seminars I have ever attended and I’m very proud to have had two such distinguished guests to present at a Metabolics seminar.
It was also a real pleasure to catch up with so many friends and colleagues that I haven’t seen for so long, as well as to make some new friends too, especially in such a wonderful venue.Read More
We’ve achieved so much as a company in the last 18 months that we wanted to reflect that by updating our logo and branding.
We feel that the new logo is more contemporary and the branding is fresh whilst continuing to look clean and clinical.Read More